Angiotensin II enhances AT(1)-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT(1), Nox1, and interleukin-18

The redox-sensitive transcription factors NF-κB and activator protein-1 (AP-1) are critical mediators of ANG II signaling. The promitogenic and promigratory factor interleukin (IL)-18 is an NF-κB- and AP-1-responsive gene. Therefore, we investigated whether ANG II-mediated smooth muscle cell (SMC) m...

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Hlavní autoři: Valente, Anthony J., Yoshida, Tadashi, Murthy, Subramanyam N., Sakamuri, Siva S. V. P., Katsuyama, Masato, Clark, Robert A., Delafontaine, Patrice, Chandrasekar, Bysani
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423158/
https://ncbi.nlm.nih.gov/pubmed/22636674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00231.2012
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