Effects of pH-sensitive chain length on release of doxorubicin from mPEG-b-PH-b-PLLA nanoparticles

BACKGROUND: Two methoxyl poly(ethylene glycol)-poly(L-histidine)-poly(L-lactide) (mPEG-PH-PLLA) triblock copolymers with different poly(L-histidine) chain lengths were synthesized. The morphology and biocompatibility of these self-assembled nanoparticles was investigated. METHODS: Doxorubicin, an an...

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Main Authors: Liu, Rong, He, Bin, Li, Dong, Lai, Yusi, Chang, Jing, Tang, James Z, Gu, Zhongwei
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2012
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423155/
https://ncbi.nlm.nih.gov/pubmed/22923987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32053
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