Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for Patched
The amino-terminal signaling domain of the Sonic hedgehog secreted protein (Shh-N), which derives from the Shh precursor through an autoprocessing reaction mediated by the carboxyl-terminal domain, executes multiple functions in embryonic tissue patterning, including induction of ventral and suppres...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.10992 |
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