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Altered β-adrenergic response in mice lacking myotonic dystrophy protein kinase (DMPK)

The protein kinase product of the gene mutated in myotonic dystrophy 1 (DMPK) is reported to play a role in cardiac pathophysiology. To gain insight into the molecular mechanisms modulated by DMPK, we characterize the impact of DMPK ablation in the context of cardiac β-adrenergic function. Our data...

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Autors principals: Llagostera, Esther, López, María Jesús Álvarez, Scimia, Cecilia, Catalucci, Daniele, Párrizas, Marcelina, Ruiz-Lozano, Pilar, Kaliman, Perla
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422658/
https://ncbi.nlm.nih.gov/pubmed/22190319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.22256
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