Role of Myotonic Dystrophy Protein Kinase (DMPK) in Glucose Homeostasis and Muscle Insulin Action

Myotonic dystrophy 1 (DM1) is caused by a CTG expansion in the 3′-unstranslated region of the DMPK gene, which encodes a serine/threonine protein kinase. One of the common clinical features of DM1 patients is insulin resistance, which has been associated with a pathogenic effect of the repeat expans...

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Autors principals: Llagostera, Esther, Catalucci, Daniele, Marti, Luc, Liesa, Marc, Camps, Marta, Ciaraldi, Theodore P., Kondo, Richard, Reddy, Sita, Dillmann, Wolfgang H., Palacin, Manuel, Zorzano, Antonio, Ruiz-Lozano, Pilar, Gomis, Ramon, Kaliman, Perla
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043489/
https://ncbi.nlm.nih.gov/pubmed/17987120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001134
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