Aberrant Epithelial-Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia

BACKGROUND & AIMS: The molecular mechanism underlying epithelial metaplasia in Barrett's esophagus remains unknown. Recognizing that Hedgehog signaling is required for early esophageal development, we sought to determine if the Hedgehog pathway is reactivated in Barrett's esophagus, an...

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Detalhes bibliográficos
Main Authors: Wang, David H., Clemons, Nicholas J., Miyashita, Tomoharu, Dupuy, Adam J., Zhang, Wei, Szczepny, Anette, Corcoran-Schwartz, Ian M., Wilburn, Daniel L., Montgomery, Elizabeth A., Wang, Jean S., Jenkins, Nancy A., Copeland, Neal A., Harmon, John W., Phillips, Wayne A., Watkins, D. Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422577/
https://ncbi.nlm.nih.gov/pubmed/20138038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.01.048
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