Bioenergetic Effects of Mitochondrial-Targeted Coenzyme Q Analogs in Endothelial Cells

Mitochondrial-targeted analogs of coenzyme Q (CoQ) are under development to reduce oxidative damage induced by a variety of disease states. However, there is a need to understand the bioenergetic effects of these agents and whether or not these effects are related to redox properties, including thei...

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Bibliographic Details
Main Authors: Fink, Brian D., Herlein, Judith A., Yorek, Mark A., Fenner, Amanda M., Kerns, Robert J., Sivitz, William I.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2012
Subjects:
Metabolism, Transport, and Pharmacogenomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422527/
https://ncbi.nlm.nih.gov/pubmed/22661629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.195586
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