Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response

Under stress conditions, pro-survival and pro-death processes are concomitantly activated and the final outcome depends on the complex crosstalk between these pathways. In most cases, autophagy functions as an early-induced cytoprotective response, favoring stress adaptation by removing damaged subc...

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Main Authors: Pagliarini, V, Wirawan, E, Romagnoli, A, Ciccosanti, F, Lisi, G, Lippens, S, Cecconi, F, Fimia, G M, Vandenabeele, P, Corazzari, M, Piacentini, M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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Original Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422474/
https://ncbi.nlm.nih.gov/pubmed/22441670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.27
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