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IMPAIRED SMALL BOWEL BARRIER INTEGRITY IN THE PRESENCE OF LUMENAL PANCREATIC DIGESTIVE ENZYMES LEADS TO CIRCULATORY SHOCK

In bowel ischemia, impaired mucosal integrity may allow intestinal pancreatic enzyme products to become systemic and precipitate irreversible shock and death. This can be attenuated by pancreatic enzyme inhibition in the small bowel lumen. It is unresolved, however, whether ischemically-mediated muc...

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Detalhes bibliográficos
Main Authors: Kistler, Erik B., Alsaigh, Tom, Chang, Marisol, Schmid-Schönbein, Geert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422435/
https://ncbi.nlm.nih.gov/pubmed/22576000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31825b1717
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