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Disruption of the Mucosal Barrier during Gut Ischemia Allows Entry of Digestive Enzymes into the Intestinal Wall

Intestinal ischemia is associated with high morbidity and mortality but the underlying mechanisms are uncertain. We hypothesize that during ischemia the intestinal mucosal barrier becomes disrupted, allowing digestive enzymes access into the intestinal wall initiating autodigestion. We used a rat mo...

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書目詳細資料
Main Authors: Chang, Marisol, Kistler, Erik B., Schmid-Schönbein, Geert W.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288241/
https://ncbi.nlm.nih.gov/pubmed/22089198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318240b59b
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