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Disruption of the Mucosal Barrier during Gut Ischemia Allows Entry of Digestive Enzymes into the Intestinal Wall

Intestinal ischemia is associated with high morbidity and mortality but the underlying mechanisms are uncertain. We hypothesize that during ischemia the intestinal mucosal barrier becomes disrupted, allowing digestive enzymes access into the intestinal wall initiating autodigestion. We used a rat mo...

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Detalhes bibliográficos
Main Authors: Chang, Marisol, Kistler, Erik B., Schmid-Schönbein, Geert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288241/
https://ncbi.nlm.nih.gov/pubmed/22089198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318240b59b
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