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Novel Somatic Mutations to PI3K Pathway Genes in Metastatic Melanoma
BACKGROUND: BRAF(V600) inhibitors have offered a new gateway for better treatment of metastatic melanoma. However, the overall efficacy of BRAF(V600) inhibitors has been lower than expected in clinical trials, and many patients have shown resistance to the drug’s effect. We hypothesized that somatic...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422312/ https://ncbi.nlm.nih.gov/pubmed/22912864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043369 |
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