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Substrate dependence of the mechanism of EcoRI endonuclease.

The mechanism of EcoRI endonuclease is substrate dependent. At 37 degrees dissociation of the enzyme-Form II DNA intermediates of ColE1 DNA and bacteriophage G4 RFI DNA is negligible. Therefore, both DNA strands with in the EcoRI sequence are cleaved during a single binding event. However, double st...

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Hlavní autoři: Rubin, R A, Modrich, P
Médium: Artigo
Jazyk:Inglês
Vydáno: 1978
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC342221/
https://ncbi.nlm.nih.gov/pubmed/211492
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