Interaction with Lipid II Induces Conformational Changes in Bovicin HC5 Structure

Bovicin HC5 is a lantibiotic produced by Streptococcus bovis HC5 that targets the cell wall precursor lipid II. An understanding of the modes of action against target bacteria can help broadening the clinical applicability of lantibiotics in human and veterinary medicine. In this study, the interact...

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Bibliographic Details
Main Authors: Paiva, Aline Dias, Irving, Nicole, Breukink, Eefjan, Mantovani, Hilário Cuquetto
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421850/
https://ncbi.nlm.nih.gov/pubmed/22687503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00295-12
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