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Role of Lipid II and Membrane Thickness in the Mechanism of Action of the Lantibiotic Bovicin HC5

Lantibiotics are antimicrobial peptides produced by Gram-positive bacteria, nisin being the most well-known member. Nisin inhibits peptidoglycan synthesis and forms pores at sensitive membranes upon interaction with lipid II, the essential bacterial cell wall precursor. Bovicin HC5, a bacteriocin pr...

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Bibliografski detalji
Glavni autori: Paiva, Aline Dias, Breukink, Eefjan, Mantovani, Hilário Cuquetto
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195046/
https://ncbi.nlm.nih.gov/pubmed/21876041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00638-11
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