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Interaction with Lipid II Induces Conformational Changes in Bovicin HC5 Structure

Bovicin HC5 is a lantibiotic produced by Streptococcus bovis HC5 that targets the cell wall precursor lipid II. An understanding of the modes of action against target bacteria can help broadening the clinical applicability of lantibiotics in human and veterinary medicine. In this study, the interact...

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Main Authors: Paiva, Aline Dias, Irving, Nicole, Breukink, Eefjan, Mantovani, Hilário Cuquetto
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421850/
https://ncbi.nlm.nih.gov/pubmed/22687503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00295-12
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