Human T-Cell Leukemia Virus Type 2 Antisense Viral Protein 2 Is Dispensable for In Vitro Immortalization but Functions To Repress Early Virus Replication In Vivo

Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 are closely related but pathogenically distinct human retroviruses. The antisense strand of the HTLV-1 genome encodes HTLV-1 basic leucine zipper (b-ZIP) protein (HBZ), a protein that inhibits Tax-mediated viral transcription, enhances T-cell pr...

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Hlavní autoři: Yin, Han, Kannian, Priya, Dissinger, Nathan, Haines, Robyn, Niewiesk, Stefan, Green, Patrick L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Transformation and Oncogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421770/
https://ncbi.nlm.nih.gov/pubmed/22623800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00717-12
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