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Human T Lymphotropic Virus Type 1 SU Residue 195 Plays a Role in Determining the Preferential CD4(+) T Cell Immortalization/Transformation Tropism

Human T lymphotropic virus type 1 (HTLV-1) mainly causes adult T cell leukemia and predominantly immortalizes/transforms CD4(+) T cells in culture. HTLV-2 is aleukemic and predominantly immortalizes/transforms CD8(+) T cells in culture. We have shown previously that the viral envelope is the genetic...

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Detalhes bibliográficos
Main Authors: Kannian, Priya, Fernandez, Soledad, Jones, Kathryn S., Green, Patrick L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754058/
https://ncbi.nlm.nih.gov/pubmed/23785214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01079-13
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