Shutoff of BZLF1 Gene Expression Is Necessary for Immortalization of Primary B Cells by Epstein-Barr Virus

The BZLF1 gene controls the switch between latent and lytic infection by Epstein-Barr virus (EBV). We previously reported that both the ZV and ZIIR elements within the BZLF1 promoter, Zp, are potent transcription silencers within the context of an intact EBV genome. We report here identification of...

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Bibliografiske detaljer
Main Authors: Yu, Xianming, McCarthy, Patrick J., Wang, Zhenxun, Gorlen, Daniel A., Mertz, Janet E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421699/
https://ncbi.nlm.nih.gov/pubmed/22623769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00234-12
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