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The ZIIR Element of the Epstein-Barr Virus BZLF1 Promoter Plays a Central Role in Establishment and Maintenance of Viral Latency

The Epstein-Barr virus (EBV) BZLF1 gene encodes the immediate-early (IE) protein Zta, which plays a central role in regulating the switch between viral latency and lytic replication. A silencing element, ZIIR, is located between the ZID and ZII positive regulatory elements in the BZLF1 promoter Zp....

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Detalhes bibliográficos
Main Authors: Yu, Xianming, McCarthy, Patrick J., Lim, Hui-Jun, Iempridee, Tawin, Kraus, Richard J., Gorlen, Daniel A., Mertz, Janet E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126197/
https://ncbi.nlm.nih.gov/pubmed/21389123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02615-10
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