Epigenetic Histone Modification of Epstein-Barr Virus BZLF1 Promoter during Latency and Reactivation in Raji Cells

The Epstein-Barr virus (EBV) predominantly establishes latent infection in B cells, and the reactivation of the virus from latency is dependent on the expression of the viral BZLF1 protein. The BZLF1 promoter (Zp) normally exhibits only low basal activity but is activated in response to chemical or...

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Bibliographic Details
Main Authors: Murata, Takayuki, Kondo, Yutaka, Sugimoto, Atsuko, Kawashima, Daisuke, Saito, Shinichi, Isomura, Hiroki, Kanda, Teru, Tsurumi, Tatsuya
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347330/
https://ncbi.nlm.nih.gov/pubmed/22357272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06768-11
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