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Either ZEB1 or ZEB2/SIP1 Can Play a Central Role in Regulating the Epstein-Barr Virus Latent-Lytic Switch in a Cell-Type-Specific Manner

We previously reported that the cellular protein ZEB1 can repress expression of the Epstein-Barr virus (EBV) BZLF1 gene in transient transfection assays by directly binding its promoter, Zp. We also reported that EBV containing a 2-bp substitution mutation in the ZEB-binding ZV element of Zp spontan...

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Detalhes bibliográficos
Main Authors: Ellis, Amy L., Wang, Zhenxun, Yu, Xianming, Mertz, Janet E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876653/
https://ncbi.nlm.nih.gov/pubmed/20375168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02706-09
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