Epstein-Barr Virus Utilizes Ikaros in Regulating Its Latent-Lytic Switch in B Cells

Ikaros is a zinc finger DNA-binding protein that regulates chromatin remodeling and the expression of genes involved in the cell cycle, apoptosis, and Notch signaling. It is a master regulator of lymphocyte differentiation and functions as a tumor suppressor in acute lymphoblastic leukemia. Neverthe...

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Main Authors: Iempridee, Tawin, Reusch, Jessica A., Riching, Andrew, Johannsen, Eric C., Dovat, Sinisa, Kenney, Shannon C., Mertz, Janet E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993812/
https://ncbi.nlm.nih.gov/pubmed/24522918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03706-13
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