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Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8
Adeno-associated viruses (AAVs) are small single-stranded DNA viruses that can package and deliver nongenomic DNA for therapeutic gene delivery. AAV8, a liver-tropic vector, has shown great promise for the treatment of hemophilia A and B. However, as with other AAV vectors, host anti-capsid immune r...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421660/ https://ncbi.nlm.nih.gov/pubmed/22593150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00218-12 |
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