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Inducible and Constitutive Activation of Two Polymorphic Promoter Alleles of the Candida albicans Multidrug Efflux Pump MDR1

Overexpression of the multidrug efflux pump MDR1 confers resistance to the antifungal drug fluconazole on Candida albicans. It has been reported that two types of MDR1 promoters exist in C. albicans and that homozygosity for the allele with higher activity may promote fluconazole resistance. We foun...

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書誌詳細
主要な著者: Sasse, Christoph, Schillig, Rebecca, Reimund, Alexandra, Merk, Julia, Morschhäuser, Joachim
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421547/
https://ncbi.nlm.nih.gov/pubmed/22615278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00264-12
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