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Multiple cis-Acting Sequences Mediate Upregulation of the MDR1 Efflux Pump in a Fluconazole-Resistant Clinical Candida albicans Isolate
Overexpression of the MDR1 gene, which encodes a multidrug efflux pump of the major facilitator superfamily, is a frequent cause of resistance to the antimycotic agent fluconazole and other metabolic inhibitors in clinical Candida albicans strains. Constitutive MDR1 overexpression in such strains is...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489804/ https://ncbi.nlm.nih.gov/pubmed/16801405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00196-06 |
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