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Chromatin measurements reveal contributions of synthesis and decay to steady-state mRNA levels

Messenger RNA levels in eukaryotes are controlled by multiple consecutive regulatory processes, which can be classified into two layers: primary transcriptional regulation at the chromosomal level and secondary, co- and post-transcriptional regulation of the mRNA. To identify the individual contribu...

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Detalhes bibliográficos
Main Authors: Tippmann, Sylvia C, Ivanek, Robert, Gaidatzis, Dimos, Schöler, Anne, Hoerner, Leslie, van Nimwegen, Erik, Stadler, Peter F, Stadler, Michael B, Schübeler, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421439/
https://ncbi.nlm.nih.gov/pubmed/22806141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2012.23
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