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Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication.

We have studied the effects of the nucleotide analogue, 2',3'-dideoxythymidine-5'-triphosphate (ddTTP) on replicative DNA synthesis in HeLa cell lysates. As previously demonstrated (1), such lysates carry out extensive DNA synthesis in vitro, at rates and in a fashion similar to in vi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Waqar, M A, Evans, M J, Huberman, J A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1978
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC342135/
https://ncbi.nlm.nih.gov/pubmed/673840
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