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Primed abortive initiation of RNA synthesis by E. coli RNA polymerase on T7 DNA. Steady state kinetic studies.

Ternary complexes of T7 DNA, RNA polymerase and the antibiotic rifampicin carry out the promoter specific abortive initiation when dinucleoside monophosphates were employed as primers. Primed abortive initiation, leading to synthesis of trinucleoside diphosphates, only occured with combinations of p...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Smagowicz, W J, Scheit, K H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1978
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342134/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/353734/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/5.6.1919
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