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The properties of ATP-analogs in initiation of RNA synthesis catalyzed by RNA polymerase from E coli.

Various base and sugar modified derivatives of ATP and UTP were used as substrate analogs for the steady state initiation reaction ATP+UTP=pppApU and the single step addition reaction ApC+ATP=ApCpA. These reactions were carried out by E. coli RNA polymerase on T7 DNA in the presence of rifampicin. T...

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Detalhes bibliográficos
Main Authors: Smagowicz, W J, Scheit, K H
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC326853/
https://ncbi.nlm.nih.gov/pubmed/7019855
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