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The properties of ATP-analogs in initiation of RNA synthesis catalyzed by RNA polymerase from E coli.
Various base and sugar modified derivatives of ATP and UTP were used as substrate analogs for the steady state initiation reaction ATP+UTP=pppApU and the single step addition reaction ApC+ATP=ApCpA. These reactions were carried out by E. coli RNA polymerase on T7 DNA in the presence of rifampicin. T...
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| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1981
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC326853/ https://ncbi.nlm.nih.gov/pubmed/7019855 |
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