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The properties of ATP-analogs in initiation of RNA synthesis catalyzed by RNA polymerase from E coli.

Various base and sugar modified derivatives of ATP and UTP were used as substrate analogs for the steady state initiation reaction ATP+UTP=pppApU and the single step addition reaction ApC+ATP=ApCpA. These reactions were carried out by E. coli RNA polymerase on T7 DNA in the presence of rifampicin. T...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Smagowicz, W J, Scheit, K H
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1981
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326853/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7019855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.10.2397
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