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Steady state kinetic studies of initiation of RNA synthesis on T7 DNA in the presence of rifampicin.

The steady state kinetics of initiation of T7 DNA transcription by RNA polymerase holo enzyme from E. coli in the presence of rifampicin and the two substrates ATP and UTP were studied. Under these conditions, the enzyme catalyzes exclusively the promotor specific synthesis of pppApU. The kinetic da...

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Autors principals: Smagowicz, J W, Scheit, K H
Format: Artigo
Idioma:Inglês
Publicat: 1977
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC343206/
https://ncbi.nlm.nih.gov/pubmed/593891
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