A microRNA network regulates expression and biosynthesis of wild-type and ΔF508 mutant cystic fibrosis transmembrane conductance regulator

Production of functional proteins requires multiple steps, including gene transcription and posttranslational processing. MicroRNAs (miRNAs) can regulate individual stages of these processes. Despite the importance of the cystic fibrosis transmembrane conductance regulator (CFTR) channel for epithel...

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Bibliografiske detaljer
Main Authors: Ramachandran, Shyam, Karp, Philip H., Jiang, Peng, Ostedgaard, Lynda S., Walz, Amy E., Fisher, John T., Keshavjee, Shaf, Lennox, Kim A., Jacobi, Ashley M., Rose, Scott D., Behlke, Mark A., Welsh, Michael J., Xing, Yi, McCray, Paul B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421220/
https://ncbi.nlm.nih.gov/pubmed/22853952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210906109
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