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Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8(+) T cell
During the primary response, the commitment of the CD8(+) T cell to Blimp-1 expression and the terminal differentiation that Blimp-1 induces must be timed so as not to impair the process of clonal expansion. We determined whether the Hippo pathway, which links cell–cell contact to differentiation in...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421161/ https://ncbi.nlm.nih.gov/pubmed/22745171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209115109 |
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