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Neonatal progeria: increased ratio of progerin to lamin A leads to progeria of the newborn

Hutchinson–Gilford progeria syndrome (HGPS) is an important model disease for premature ageing. Affected children appear healthy at birth, but develop the first symptoms during their first year of life. They die at an average age of 13 years, mostly because of myocardial infarction or stroke. Classi...

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Autori principali: Reunert, Janine, Wentzell, Rüdiger, Walter, Michael, Jakubiczka, Sibylle, Zenker, Martin, Brune, Thomas, Rust, Stephan, Marquardt, Thorsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421121/
https://ncbi.nlm.nih.gov/pubmed/22419169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.36
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