Lamin microaggregates lead to altered mechanotransmission in progerin-expressing cells

The nuclear lamina is a meshwork of intermediate filament proteins, and lamin A is the primary mechanical protein. An altered splicing of lamin A, known as progerin, causes the disease Hutchinson-Gilford progeria syndrome. Progerin-expressing cells have altered nuclear shapes and stiffened nuclear l...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Danielsson, Brooke E., Tieu, Katie V., Bathula, Kranthidhar, Armiger, Travis J., Vellala, Pragna S., Taylor, Rebecca E., Dahl, Kris Noel, Conway, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529416/
https://ncbi.nlm.nih.gov/pubmed/32816594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2020.1802906
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados