Measurement of 5-HT(1A) receptor density and in-vivo binding parameters of [(18)F]mefway in the nonhuman primate

The goal of this work was to characterize the in-vivo behavior of [(18)F]mefway as a suitable positron emission tomography (PET) radiotracer for the assay of 5-hydroxytryptamine(1A) (5-HT(1A)) receptor density (B(max)). Six rhesus monkeys were studied using a multiple-injection (M-I) protocol consis...

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Autors principals: Wooten, Dustin W, Hillmer, Ansel T, Moirano, Jeffrey M, Ahlers, Elizabeth O, Slesarev, Maxim, Barnhart, Todd E, Mukherjee, Jogeshwar, Schneider, Mary L, Christian, Bradley T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421091/
https://ncbi.nlm.nih.gov/pubmed/22472611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.43
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