12-LIPOXYGENASE AND THE REGULATION OF HYPOXIA-INDUCIBLE FACTOR IN PROSTATE CANCER CELLS

12-lipoxygenase, an arachidonic acid metabolizing enzyme of the lipoxygenase pathway, has been implicated as a major factor in promoting prostate cancer progression and metastasis. The ability of 12-LOX to aggravate the disease was linked to its proangiogenic role. Recent studies clearly demonstrate...

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Main Authors: Krishnamoorthy, Sriram, Jin, Rongxian, Cai, Yinlong, Maddipati, Krishna Rao, Nie, Daotai, Pages, Gilles, Tucker, Stephanie C., Honn, Kenneth V.
格式: Artigo
語言:Inglês
出版: 2010
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420817/
https://ncbi.nlm.nih.gov/pubmed/20303950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.03.005
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