Downregulation of Vascular Endothelial Growth Factor and Induction of Tumor Dormancy by 15-lipoxygenase-2 in Prostate Cancer

The enzyme 15-lipoxygenase-2 (15-LOX-2) utilizes arachidonic acid, a polyunsaturated fatty acid, to synthesize 15(S)-hydroxyeicosatetraenoic acid (HETE). Abundantly expressed in normal prostate epithelium but frequently suppressed in the cancerous tissues, 15-LOX-2 has been suggested as a functional...

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Detalhes bibliográficos
Main Authors: Tang, Yong, Wang, Man-Tzu, Chen, Yakun, Yang, Dianer, Che, Mingxin, Honn, Kenneth V, Akers, Gregory D, Johnson, Stephen R, Nie, Daotai
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913418/
https://ncbi.nlm.nih.gov/pubmed/19089921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24118
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