Halogenation of 4-Hydroxy/Amino-3-methoxyphenyl Acetamide TRPV1 Agonists Showed Enhanced Antagonism to Capsaicin

As an extension of our analysis of the effect of halogenation on thiourea TRPV1 agonists, we have now modified selected 4-hydroxy(or 4-amino)-3-methoxyphenyl acetamide TRPV1 agonists by 5- or 6-halogenation on the aromatic A-region and evaluated them for potency for TRPV1 binding and regulation and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kang, Dong Wook, Kim, Yong Soo, Lim, Kwang Su, Kim, Myeong Seop, Lee, Jeewoo, Pearce, Larry V., Pavlyukovets, Vladimir A., Tao, Andy K., Lang-Kuhs, Krystle A., Blumberg, Peter M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420354/
https://ncbi.nlm.nih.gov/pubmed/20937561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.09.001
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन