Thymocytes may persist and differentiate without any input from bone marrow progenitors

Thymus transplants can correct deficiencies of the thymus epithelium caused by the complete DiGeorge syndrome or FOXN1 mutations. However, thymus transplants were never used to correct T cell–intrinsic deficiencies because it is generally believed that thymocytes have short intrinsic lifespans. This...

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Bibliografske podrobnosti
Main Authors: Peaudecerf, Laetitia, Lemos, Sara, Galgano, Alessia, Krenn, Gerald, Vasseur, Florence, Di Santo, James P., Ezine, Sophie, Rocha, Benedita
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Brief Definitive Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420331/
https://ncbi.nlm.nih.gov/pubmed/22778388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120845
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