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Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury

BACKGROUND: Perinatal brain injury is complex and often associated with both inflammation and hypoxia-ischaemia (HI). In adult inflammatory brain injury models, therapies to increase acetylation are efficacious in reducing inflammation and cerebral injury. Our aim in the present study was to examine...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fleiss, Bobbi, Nilsson, Marie KL, Blomgren, Klas, Mallard, Carina
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420244/
https://ncbi.nlm.nih.gov/pubmed/22512781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-70
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