Effects of Alcohol on Histone Deacetylase 2 (HDAC2) and the Neuroprotective Role of Trichostatin A (TSA)

BACKGROUND: Previous studies have implicated histone deacetylases (HDACs) and HDAC inhibitors (HDIs) such as Trichostatin A (TSA) in the regulation of gene expression during drug addiction. Furthermore, an increase in HDAC activity has been linked to neurodegeneration. Alcohol has also been shown to...

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Hlavní autoři: Agudelo, Marisela, Gandhi, Nimisha, Saiyed, Zainulabedin, Pichili, Vijaya, Thangavel, Samikkannu, Khatavkar, Pradnya, Yndart-Arias, Adriana, Nair, Madhavan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128172/
https://ncbi.nlm.nih.gov/pubmed/21447001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01492.x
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