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Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS

HIV-1 clades (subtypes) differentially contribute to the neuropathogenesis of HIV-associated dementia (HAD) in neuroAIDS. HIV-1 envelop protein, gp120, plays a major role in neuronal function. It is not well understood how these HIV-1 clades exert these neuropathogenic differences. The N-methyl-D-as...

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Détails bibliographiques
Publié dans:J Neurovirol
Auteurs principaux: Samikkannu, Thangavel, Agudelo, Marisela, Gandhi, Nimisha, Reddy, Pichili V. B., Saiyed, Zainulabedin M., Nwankwo, Donald, Nair, Madhavan P. N.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737634/
https://ncbi.nlm.nih.gov/pubmed/21491143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-011-0026-5
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