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Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite

Through rapid genetic adaptation and natural selection, the Plasmodium falciparum parasite—the deadliest of those that cause malaria—is able to develop resistance to antimalarial drugs, thwarting present efforts to control it. Genome-wide association studies (GWAS) provide a critical hypothesis-gene...

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書誌詳細
主要な著者: Park, Daniel J., Lukens, Amanda K., Neafsey, Daniel E., Schaffner, Stephen F., Chang, Hsiao-Han, Valim, Clarissa, Ribacke, Ulf, Van Tyne, Daria, Galinsky, Kevin, Galligan, Meghan, Becker, Justin S., Ndiaye, Daouda, Mboup, Souleymane, Wiegand, Roger C., Hartl, Daniel L., Sabeti, Pardis C., Wirth, Dyann F., Volkman, Sarah K.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420184/
https://ncbi.nlm.nih.gov/pubmed/22826220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210585109
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