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Fractalkine Mediates Communication between Pathogenic Proteins and Microglia: Implications of Anti-Inflammatory Treatments in Different Stages of Neurodegenerative Diseases

The role of inflammation in neurodegenerative diseases has been widely demonstrated. Intraneuronal protein accumulation may regulate microglial activity via the fractalkine (CX3CL1) signaling pathway that provides a mechanism through which neurons communicate with microglia. CX3CL1 levels fluctuate...

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Détails bibliographiques
Auteurs principaux: Desforges, Nicole M., Hebron, Michaeline L., Algarzae, Norah K., Lonskaya, Irina, Moussa, Charbel E.-H.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420133/
https://ncbi.nlm.nih.gov/pubmed/22919540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/345472
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