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RECQ1 plays a distinct role in cellular response to oxidative DNA damage

RECQ1 is the most abundant RecQ homolog in humans but its functions have remained mostly elusive. Biochemically, RECQ1 displays distinct substrate specificities from WRN and BLM, indicating that these RecQ helicases likely perform non-overlapping functions. Our earlier work demonstrated that RECQ1-d...

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Detalhes bibliográficos
Main Authors: Sharma, Sudha, Phatak, Pornima, Stortchevoi, Alexei, Jasin, Maria, LaRocque, Jeannine R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420015/
https://ncbi.nlm.nih.gov/pubmed/22542292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.04.003
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