Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation

BACKGROUND: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits the ability to profile mRNA expression, we explored factors predicting the success of mRNA expression profiling of FFPE material and investigated an approach to overcome the limitation. METHODS: Bladder (n=140, stor...

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Detalles Bibliográficos
Autores principales: Hall, J S, Taylor, J, Valentine, H R, Irlam, J J, Eustace, A, Hoskin, P J, Miller, C J, West, C M L
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419950/
https://ncbi.nlm.nih.gov/pubmed/22805332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.294
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