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Co-transcriptional degradation of aberrant pre-mRNA by Xrn2

Eukaryotic protein-coding genes are transcribed as pre-mRNAs that are matured by capping, splicing and cleavage and polyadenylation. Although human pre-mRNAs can be long and complex, containing multiple introns and many alternative processing sites, they are usually processed co-transcriptionally. M...

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Bibliografski detalji
Glavni autori: Davidson, Lee, Kerr, Alastair, West, Steven
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365414/
https://ncbi.nlm.nih.gov/pubmed/22522706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.101
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