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Co-transcriptional degradation of aberrant pre-mRNA by Xrn2
Eukaryotic protein-coding genes are transcribed as pre-mRNAs that are matured by capping, splicing and cleavage and polyadenylation. Although human pre-mRNAs can be long and complex, containing multiple introns and many alternative processing sites, they are usually processed co-transcriptionally. M...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365414/ https://ncbi.nlm.nih.gov/pubmed/22522706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.101 |
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