Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation

BACKGROUND: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits the ability to profile mRNA expression, we explored factors predicting the success of mRNA expression profiling of FFPE material and investigated an approach to overcome the limitation. METHODS: Bladder (n=140, stor...

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Detalhes bibliográficos
Main Authors: Hall, J S, Taylor, J, Valentine, H R, Irlam, J J, Eustace, A, Hoskin, P J, Miller, C J, West, C M L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419950/
https://ncbi.nlm.nih.gov/pubmed/22805332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.294
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